RAD21_HUMAN   O60216


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UniProt:O60216

Recommended name:Double-strand-break repair protein rad21 homolog

EC number:

Alternative names:(hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog)

Cleaved into:64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)

GeneID:5885

Gene names  (primary ):RAD21

Gene names  (synonym ):HR21 KIAA0078 NXP1 SCC1

Gene names  (ORF ):

Length:631

Mass:71690

Sequence:MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII

Tissue specificity:Expressed in the gut (at protein level). {ECO:0000269|PubMed:25575569}.

Induction:

Developmental stage:Regulated in a cell cycle-dependent manner: expression increases in late S phase and reaches maximum in G2 at the nucleotide level (PubMed:8812457). Not regulated during the cell cycle (at protein level) (PubMed:11073952). {ECO:0000269|PubMed:11073952, ECO:0000269|PubMed:8812457}.

Protein families:Rad21 family


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