RAD21_HUMAN O60216
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UniProt:O60216
Recommended name:Double-strand-break repair protein rad21 homolog
EC number:
Alternative names:(hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog)
Cleaved into:64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)
GeneID:5885
Gene names (primary ):RAD21
Gene names (synonym ):HR21 KIAA0078 NXP1 SCC1
Gene names (ORF ):
Length:631
Mass:71690
Sequence:MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII
Tissue specificity:Expressed in the gut (at protein level). {ECO:0000269|PubMed:25575569}.
Induction:
Developmental stage:Regulated in a cell cycle-dependent manner: expression increases in late S phase and reaches maximum in G2 at the nucleotide level (PubMed:8812457). Not regulated during the cell cycle (at protein level) (PubMed:11073952). {ECO:0000269|PubMed:11073952, ECO:0000269|PubMed:8812457}.
Protein families:Rad21 family